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Real-World Outcomes Among Medicare Beneficiaries Treated With First-Line Bruton Tyrosine Kinase Inhibitors for Chronic Lymphocytic Leukemia

Real-World Outcomes Among Medicare Beneficiaries Treated With First-Line Bruton Tyrosine Kinase Inhibitors for Chronic Lymphocytic Leukemia

AI Briefing

  • • Zanubrutinib showed longer real-world treatment duration and time to next treatment in older CLL patients.
  • • Zanubrutinib was associated with better overall survival compared to acalabrutinib and ibrutinib.
  • • Study analysis was based on Medicare Fee-for-Service data.

Source Summary

Daniel A. Ermann, MD, reviews a large Medicare Fee-for-Service analysis showing zanubrutinib was associated with longer real-world treatment duration, time to next treatment, and overall survival vs acalabrutinib and ibrutinib in older patients with first-line CLL.

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